despite 与 despite of 有啥区别,两者分别在什么情况下用?

没有despite of,只有inspite of .
"despite"后面接的一定是名词,例子：Despite all our efforts ,we still lost the game.尽管我们做了全部的努力,但还是输了游戏.
"inspite of"后面也是名词,例子：inspite of all our efforts ,we still lost the game .意思是一样的.despite of 不管；不顾有道词典上的解释 例句：The plane took off despite of the heavy rain这个怎么解释？despite 后面跟一个句子，despite of 后面跟着一个名词 despite和 in spite of一样